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Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease

The heart is a highly specialized organ with essential function for the organism throughout life. The significance of DNA methylation in shaping the phenotype of the heart remains only partially known. Here we generate and analyse DNA methylomes from highly purified cardiomyocytes of neonatal, adult...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Gilsbach, Ralf, Preissl, Sebastian, Grüning, Björn A., Schnick, Tilman, Burger, Lukas, Benes, Vladimir, Würch, Andreas, Bönisch, Ulrike, Günther, Stefan, Backofen, Rolf, Fleischmann, Bernd K., Schübeler, Dirk, Hein, Lutz
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Pub. Group 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220495/
https://ncbi.nlm.nih.gov/pubmed/25335909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6288
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