Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease

The heart is a highly specialized organ with essential function for the organism throughout life. The significance of DNA methylation in shaping the phenotype of the heart remains only partially known. Here we generate and analyse DNA methylomes from highly purified cardiomyocytes of neonatal, adult...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Gilsbach, Ralf, Preissl, Sebastian, Grüning, Björn A., Schnick, Tilman, Burger, Lukas, Benes, Vladimir, Würch, Andreas, Bönisch, Ulrike, Günther, Stefan, Backofen, Rolf, Fleischmann, Bernd K., Schübeler, Dirk, Hein, Lutz
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220495/
https://ncbi.nlm.nih.gov/pubmed/25335909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6288
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