Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease

The heart is a highly specialized organ with essential function for the organism throughout life. The significance of DNA methylation in shaping the phenotype of the heart remains only partially known. Here we generate and analyse DNA methylomes from highly purified cardiomyocytes of neonatal, adult...

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Publicado en:Nat Commun
Autores principales: Gilsbach, Ralf, Preissl, Sebastian, Grüning, Björn A., Schnick, Tilman, Burger, Lukas, Benes, Vladimir, Würch, Andreas, Bönisch, Ulrike, Günther, Stefan, Backofen, Rolf, Fleischmann, Bernd K., Schübeler, Dirk, Hein, Lutz
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Pub. Group 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220495/
https://ncbi.nlm.nih.gov/pubmed/25335909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6288
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