Controlling for population structure and genotyping platform bias in the eMERGE multi-institutional biobank linked to electronic health records

Combining samples across multiple cohorts in large-scale scientific research programs is often required to achieve the necessary power for genome-wide association studies. Controlling for genomic ancestry through principal component analysis (PCA) to address the effect of population stratification i...

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Detaylı Bibliyografya
Yayımlandı:Front Genet
Asıl Yazarlar: Crosslin, David R., Tromp, Gerard, Burt, Amber, Kim, Daniel S., Verma, Shefali S., Lucas, Anastasia M., Bradford, Yuki, Crawford, Dana C., Armasu, Sebastian M., Heit, John A., Hayes, M. Geoffrey, Kuivaniemi, Helena, Ritchie, Marylyn D., Jarvik, Gail P., de Andrade, Mariza
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2014
Konular:
Genetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220165/
https://ncbi.nlm.nih.gov/pubmed/25414722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00352
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