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Nucleotide Bound to rab11a Controls Localization in Rod Cells But Not Interaction with Rhodopsin
Precise vectorial transport of rhodopsin is essential for rod photoreceptor health and function. Mutations that truncate or extend the C terminus of rhodopsin disrupt this transport, and lead to retinal degeneration and blindness in human patients and in mouse models. Here we show that such mutation...
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| Publié dans: | J Neurosci |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4220021/ https://ncbi.nlm.nih.gov/pubmed/25378153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1943-14.2014 |
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