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Mycobacterium tuberculosis PE25/PPE41 protein complex induces necrosis in macrophages: Role in virulence and disease reactivation?

Necrotic cell death during TB infection is an important prerequisite for bacterial dissemination and virulence. The underlying mechanisms and the bacterial factors involved therein are not well understood. The Mycobacterium tuberculosis (M. tuberculosis) co-operonic PE25/PPE41 protein complex, simil...

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Bibliografiske detaljer
Udgivet i:FEBS Open Bio
Main Authors: Tundup, Smanla, Mohareer, Krishnaveni, Hasnain, Seyed E.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219985/
https://ncbi.nlm.nih.gov/pubmed/25379378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.09.001
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