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Mycobacterium tuberculosis PE25/PPE41 protein complex induces necrosis in macrophages: Role in virulence and disease reactivation?

Necrotic cell death during TB infection is an important prerequisite for bacterial dissemination and virulence. The underlying mechanisms and the bacterial factors involved therein are not well understood. The Mycobacterium tuberculosis (M. tuberculosis) co-operonic PE25/PPE41 protein complex, simil...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Tundup, Smanla, Mohareer, Krishnaveni, Hasnain, Seyed E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219985/
https://ncbi.nlm.nih.gov/pubmed/25379378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.09.001
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