“Glowing Head” Mice: A Genetic Tool Enabling Reliable Preclinical Image-Based Evaluation of Cancers in Immunocompetent Allografts

Preclinical therapeutic assessment currently relies on the growth response of established human cell lines xenografted into immunocompromised mice, a strategy that is generally not predictive of clinical outcomes. Immunocompetent genetically engineered mouse (GEM)-derived tumor allograft models offe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Day, Chi-Ping, Carter, John, Ohler, Zoe Weaver, Bonomi, Carrie, El Meskini, Rajaa, Martin, Philip, Graff-Cherry, Cari, Feigenbaum, Lionel, Tüting, Thomas, Van Dyke, Terry, Hollingshead, Melinda, Merlino, Glenn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219677/
https://ncbi.nlm.nih.gov/pubmed/25369133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109956
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