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Design and Analysis of Hammerhead Ribozyme Activity Against an Artificial Gene Target

In vitro cleavage assays are routinely conducted to properly assess the catalytic activity of hammerhead ribozymes (HHR) against target RNA molecules like the dengue virus RNA genomes. These experiments are performed for initial assessment of HHR catalysis in a cell-free system and have been simplif...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Carter, James, Nawtaisong, Pruksa, Balaraman, Velmurugan, Fraser, Malcolm J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219533/
https://ncbi.nlm.nih.gov/pubmed/24318886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-730-3_5
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