Novel role of the serine protease inhibitor elafin in gluten-related disorders

OBJECTIVES: Elafin, an endogenous serine protease inhibitor, modulates colonic inflammation. We investigated the role of elafin in celiac disease (CD) using human small intestinal tissues and in vitro assays of gliadin deamidation. We also investigated potential beneficial effects of elafin in a mou...

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Bibliografske podrobnosti
izdano v:Am J Gastroenterol
Main Authors: Galipeau, Heather J., Wiepjes, Michelle, Motta, Jean-Paul, Schulz, Jessica D., Jury, Jennifer, Natividad, Jane M., Pinto-Sanchez, Ines, Sinclair, Daniel, Rousset, Perrine, Martin-Rosique, Rebeca, Bermudez-Humaran, Luis, Leroux, Jean Christophe, Murray, Joseph, Smecuol, Edgardo, Bai, Julio C., Vergnolle, Nathalie, Langella, Philippe, Verdu, Elena F
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219532/
https://ncbi.nlm.nih.gov/pubmed/24710505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2014.48
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