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Age of Onset and Effect Size in Genome-Wide Association Studies

BACKGROUND: Genome-wide association studies (GWAS) have identified many susceptibility loci for complex traits, but have not identified the majority of the genetic contribution to common diseases. We explored whether the magnitude of associations detected in GWAS and, therefore, the likelihood of de...

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Detalles Bibliográficos
Publicado en:Birth Defects Res A Clin Mol Teratol
Autores principales: Agopian, A.J., Eastcott, Lisa M., Mitchell, Laura E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219508/
https://ncbi.nlm.nih.gov/pubmed/22933422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23066
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