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Pulsed high intensity focused ultrasound increases penetration and therapeutic efficacy of monoclonal antibodies in murine xenograft tumors

The success of radioimmunotherapy for solid tumors remains elusive due to poor biodistribution and insufficient tumor accumulation, in part, due to the unique tumor microenvironment resulting in heterogeneous tumor antibody distribution. Pulsed high intensity focused ultrasound (pulsed-HIFU) has pre...

詳細記述

保存先:
書誌詳細
出版年:J Control Release
主要な著者: Wang, Shutao, Shin, In Soo, Hancock, Hilary, Jang, Beom-su, Kim, Hyung-sub, Lee, Sang Myung, Zderic, Vesna, Frenkel, Victor, Pastan, Ira, Paik, Chang H., Dreher, Matthew R.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219504/
https://ncbi.nlm.nih.gov/pubmed/22732476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.06.025
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