COX-2-Derived PGE2 Promotes Injury-induced Vascular Neointimal Hyperplasia through the EP3 Receptor

RATIONALE: Vascular smooth muscle cell (VSMC) migration and proliferation are the hallmarks of restenosis pathogenesis after angioplasty. Cyclooxygenase (COX)-derived prostaglandin (PG)E(2) is implicated in the vascular remodeling response to injury. However, its precise molecular role remains unkno...

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Publicat a:Circ Res
Autors principals: Zhang, Jian, Zou, Fangfang, Tang, Juan, Zhang, Qianqian, Gong, Yanjun, Wang, Qingsong, Shen, Yujun, Xiong, Lixia, Breyer, Richard, Lararus, Michael, Funk, Colin D., Yu, Ying
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219358/
https://ncbi.nlm.nih.gov/pubmed/23595951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301033
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