PT-04 PRELIMINARY RESULTS OF A PHASE I/II STUDY OF INTRA-ARTERIAL CHEMOTHERAPY WITH OSMOTIC BLOOD-BRAIN BARRIER DISRUPTION FOR PATIENTS WITH RECURRENT OR PROGRESSIVE CNS EMBRYONAL OR GERM CELL TUMORS

INTRODUCTION: Patients with refractory or recurrent CNS embryonal or germ cell tumors have poor prognosis and survivors suffer neuropsychological sequalae from radiotherapy and ototoxicity from chemotherapy. Prior retrospective studies suggest intra-arterial (IA) chemotherapy in conjunction with blo...

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Main Authors: Das, Paramita, Guillaume, Daniel, Nazemi, Kellie, Moertel, Christopher, Doolittle, Nancy, Lacy, Cynthia, Neuwelt, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218461/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou266.4
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