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NT-17 TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) WITH AN ONCOLYTIC MEASLES VIRUS IN COMBINATION WITH INHIBITORS OF THE PI3-KINASE PATHWAY

BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) is a highly malignant pediatric brainstem tumor with less than 10% of patients surviving beyond 2 years. Surgical resection of this diffusely infiltrative tumor is not possible, radiation therapy is palliative not curative, and chemotherapy is inef...

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Библиографические подробности
Главные авторы: Lal, Sangeet, Lawrence, Samuel, Raffel, Corey
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218425/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou265.16
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