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NI-39 INITIAL EVALUATION OF AN ADENOSINE RECEPTOR AGONIST'S ABILITY TO TRANSIENTLY DISRUPT THE BLOOD BRAIN BARRIER (BBB) IN PATIENTS WITH IN NORMAL BRAINS

BACKGROUND: Regadenoson is an FDA approved adenosine receptor agonist which transiently disrupts the BBB in rodents allowing systemically administered high molecular weight dextran (MW 70kD) to enter brain parenchyma. This agent is used clinically for cardiac stress tests in patients unable to exerc...

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Detalhes bibliográficos
Main Authors: Jackson, Sadhana, Lodge, Martin, Piotrowski, Anna, Wahl, Richard, Grossman, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218364/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou264.37
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