MR-02 A GENOME-WIDE miRNA SCREEN REVEALED MIR-603 AS A MGMT-REGULATING miRNA IN GLIOBLASTOMAS

MGMT expression is a critical determinant for therapeutic resistance to DNA alkylating agents. We previously demonstrated that MGMT expression is post-transcriptionally regulated by miR-181d and other miRNAs. Here, we performed a genome-wide screen to identify MGMT regulating miRNAs. Candidate miRNA...

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Autori principali: Kushwaha, Deepa, Ramakrishnan, Valya, Ng, Kimberly, Steed, Tyler, Nguyen, Thien, Futalan, Diahnn, Akers, Johnny, Tao, Jiang, Chowdhury, Dipanjan, Carter, Bob, Chen, Clark
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218313/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou262.2
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