ME-20 CULTURE OF HUMAN GBM CELLS ON ECM-MIMICKING CHITOSAN-HYALURONIC ACID SCAFFOLDS INCREASES MALIGNANCY AND DRUG RESISTANCE

Glioblastoma multiforme (GBM) is the most aggressive and deadly malignant primary brain tumor in humans. Development of therapeutics requires extensive screening; however, many therapeutics evaluated with 2D in vitro cultures does not translate well to similar in vivo studies and suffer from lower e...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Wang, Kui, Florczyk, Stephen, Kievit, Forrest, Zhang, Miqin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218303/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou261.19
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