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Porous chitosan-hyaluronic acid scaffolds as a mimic of glioblastoma microenvironment ECM

Cancer therapeutics are developed through extensive screening; however, many therapeutics evaluated with 2D in vitro cultures during pre-clinical trials suffer from lower efficacy in patients. Replicating the in vivo tumor microenvironment in vitro with three-dimensional (3D) porous scaffolds offers...

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Detalhes bibliográficos
Main Authors: Florczyk, Stephen J., Wang, Kui, Jana, Soumen, Wood, David L., Sytsma, Samara K., Sham, Jonathan, Kievit, Forrest M., Zhang, Miqin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843957/
https://ncbi.nlm.nih.gov/pubmed/24075410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.09.034
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