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Chitosan-Alginate Scaffold Culture System for Hepatocellular Carcinoma Increases Malignancy and Drug Resistance

PURPOSE: Hepatocellular carcinoma (HCC) is a prevalent solid malignancy. Critically needed discovery of new therapeutics has been hindered by lack of an in vitro cell culture system that can effectively represent the in vivo tumor microenvironment. To address this need, a 3D in vitro HCC model was d...

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Detalhes bibliográficos
Main Authors: Leung, Matthew, Kievit, Forrest M., Florczyk, Stephen J., Veiseh, Omid, Wu, Jennifer, Park, James O., Zhang, Miqin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917619/
https://ncbi.nlm.nih.gov/pubmed/20585843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0198-3
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