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Chitosan-Alginate Scaffold Culture System for Hepatocellular Carcinoma Increases Malignancy and Drug Resistance

PURPOSE: Hepatocellular carcinoma (HCC) is a prevalent solid malignancy. Critically needed discovery of new therapeutics has been hindered by lack of an in vitro cell culture system that can effectively represent the in vivo tumor microenvironment. To address this need, a 3D in vitro HCC model was d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Leung, Matthew, Kievit, Forrest M., Florczyk, Stephen J., Veiseh, Omid, Wu, Jennifer, Park, James O., Zhang, Miqin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917619/
https://ncbi.nlm.nih.gov/pubmed/20585843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0198-3
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