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ME-20 CULTURE OF HUMAN GBM CELLS ON ECM-MIMICKING CHITOSAN-HYALURONIC ACID SCAFFOLDS INCREASES MALIGNANCY AND DRUG RESISTANCE
Glioblastoma multiforme (GBM) is the most aggressive and deadly malignant primary brain tumor in humans. Development of therapeutics requires extensive screening; however, many therapeutics evaluated with 2D in vitro cultures does not translate well to similar in vivo studies and suffer from lower e...
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Veröffentlicht in: | Neuro Oncol |
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Hauptverfasser: | , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Oxford University Press
2014
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218303/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou261.19 |
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