IT-35 cGMP MANUFACTURING OF EX VIVO EXPANDED TUMOR-SPECIFIC T CELLS AND AMPLIFIED TUMOR RNA-PULSED DC VACCINES TARGETING GLIOBLASTOMA AND MEDULLOBLASTOMA

BACKGROUND: Adoptive cellular therapy using transfer of tumor-specific lymphocytes has emerged as a potent strategy for treatment of advanced and refractory malignancies. We have employed the use of total tumor RNA (TTRNA)-pulsed DCs in the ex vivo expansion of tumor-specific lymphocytes for use in...

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Detaylı Bibliyografya
Asıl Yazarlar: Yegorov, Oleg, Dechkovskaia, Anjelika, Drake, Jeffery, Cleaver, Brian D., Clement, Nathalie, Huang, Jianping, Mitchell, Duane A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218253/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou258.33
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