IT-34 PILOT STUDY OF COMBINATION OF ANTITUMOR IMMUNOTHERAPY TARGETED AGAINST CYTOMEGALOVIRUS (CMV) PLUS REGULATORY T-CELL INHIBITION IN PATIENTS WITH NEWLY-DIAGNOSED GLIOBLASTOMA MULTIFORME (GBM)

BACKGROUND: Despite aggressive surgery, high-dose focused radiation, and multimechanistic chemotherapy, malignant gliomas (MG) remain almost universally fatal. The inherent biologic specificity of immunotherapy offers the prospect of targeting neoplastic cells more precisely. Dendritic cells (DCs) a...

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Autors principals: Vlahovic, Gordana, Archer, Gerald, Lally-Goss, Denise, Reap, Elizabeth, Batich, Kristen, Desjardins, Annick, Peters, Katherine, Ranjan, Tulika, Healy, Patrick, Herndon, James, Friedman, Allan, Friedman, Henry, Bigner, Darell, Sampson, John
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218252/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou258.32
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