IT-34 PILOT STUDY OF COMBINATION OF ANTITUMOR IMMUNOTHERAPY TARGETED AGAINST CYTOMEGALOVIRUS (CMV) PLUS REGULATORY T-CELL INHIBITION IN PATIENTS WITH NEWLY-DIAGNOSED GLIOBLASTOMA MULTIFORME (GBM)

BACKGROUND: Despite aggressive surgery, high-dose focused radiation, and multimechanistic chemotherapy, malignant gliomas (MG) remain almost universally fatal. The inherent biologic specificity of immunotherapy offers the prospect of targeting neoplastic cells more precisely. Dendritic cells (DCs) a...

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Main Authors: Vlahovic, Gordana, Archer, Gerald, Lally-Goss, Denise, Reap, Elizabeth, Batich, Kristen, Desjardins, Annick, Peters, Katherine, Ranjan, Tulika, Healy, Patrick, Herndon, James, Friedman, Allan, Friedman, Henry, Bigner, Darell, Sampson, John
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218252/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou258.32
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