GE-04 MGMT METHYLATION IS A POSITIVE PROGNOSTIC MARKER IN PATIENTS WITH ANAPLASTIC ASTROCYTOMA TREATED WITH CONCURRENT TEMOZOLOMIDE AND RADIATION

BACKGROUND: Concurrent radiation (RT) and temozolomide (TMZ) has been accepted as standard first-line therapy for glioblastoma since publication of results of the phase III EORTC/NCIC trial in 2005. In the same NEJM issue, data were presented which showed the prognostic significance of MGMT methylat...

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Autori principali: Blumenthal, Deborah, Bokstein, Felix, Zelikovitsh, Bracha, Mordechai, Anat, Lossos, Alexander, Taliansky, Alisa, Zach, Lior, Tzuk-Shina, Tzahallah, Lavon, Iris
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218206/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou256.4
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