Effectiveness of interferon-beta and temozolomide combination therapy against temozolomide-refractory recurrent anaplastic astrocytoma

BACKGROUND: Malignant gliomas recur even after extensive surgery and chemo-radiotherapy. Although a relatively novel chemotherapeutic agent, temozolomide (TMZ), has demonstrated promising activity against recurrent glioma, the effects last only a few months and drug resistance develops thereafter in...

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Main Authors: Fujimaki, Takamitsu, Ishii, Hisato, Matsuno, Akira, Arai, Hajime, Nakagomi, Tadayoshi
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
Assuntos:
Case Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976115/
https://ncbi.nlm.nih.gov/pubmed/17683572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-5-89
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