GE-37 INTEGRATED GENOMIC ANALYSIS OF LOW GRADE GLIOMA AND GLIOBLASTOMA REVEALS MOLECULAR STRATIFICATION BY IDH STATUS ACROSS GRADES AND HISTOLOGIES

TCGA has performed comprehensive molecular characterization of glioblastoma (GBM) and diffuse low grade glioma (LGG), which suggested heterogeneity in clinical diagnosis: GBM with isocitrate dehydrogenase (IDH) gene mutations corresponded with a hypermethylator/G-CIMP phenotype and relatively favora...

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Bibliografiske detaljer
Main Authors: Verhaak, Roel, Iavarone, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218202/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou256.36
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