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GE-37 INTEGRATED GENOMIC ANALYSIS OF LOW GRADE GLIOMA AND GLIOBLASTOMA REVEALS MOLECULAR STRATIFICATION BY IDH STATUS ACROSS GRADES AND HISTOLOGIES

TCGA has performed comprehensive molecular characterization of glioblastoma (GBM) and diffuse low grade glioma (LGG), which suggested heterogeneity in clinical diagnosis: GBM with isocitrate dehydrogenase (IDH) gene mutations corresponded with a hypermethylator/G-CIMP phenotype and relatively favora...

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Detalhes bibliográficos
Main Authors: Verhaak, Roel, Iavarone, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218202/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou256.36
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