GE-30 OLIGOASTROCYTOMA DOES NOT EXIST: IN-SITU MOLECULAR GENETICS FAVORS CLASSIFICATION AS EITHER OLIGODENDROGLIOMA OR ASTROCYTOMA

Astrocytoma and oligodendroglioma are histologically and genetically well-defined entities. The majority of astrocytomas harbor concurrent TP53 and ATRX mutations while most oligodendrogliomas carry the 1p/19q co-deletion. Both entities share high frequencies of IDH mutations. In contrast, oligoastr...

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Hauptverfasser: Sahm, Felix, Reuss, David, Koelsche, Christian, Capper, David, Schittenhelm, Jens, Heim, Stefanie, Herold-Mende, Christel, Wick, Wolfgang, Mueller, Wolf, Hartmann, Christian, Paulus, Wener, von Deimling, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218194/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou256.29
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