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GE-30 OLIGOASTROCYTOMA DOES NOT EXIST: IN-SITU MOLECULAR GENETICS FAVORS CLASSIFICATION AS EITHER OLIGODENDROGLIOMA OR ASTROCYTOMA
Astrocytoma and oligodendroglioma are histologically and genetically well-defined entities. The majority of astrocytomas harbor concurrent TP53 and ATRX mutations while most oligodendrogliomas carry the 1p/19q co-deletion. Both entities share high frequencies of IDH mutations. In contrast, oligoastr...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218194/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou256.29 |
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