P09.09 Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas

Gemistocytic astrocytoma represents a subgroup of diffuse astrocytic glioma, defined by presence of “a conspicuous, though variable, fraction of gemistocytic neoplastic astrocytes”. Higher frequencies of PTEN and TP53 mutations, alterations in the methylation of ERCC and RRAS, and more rapid progres...

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Publicat a:Neuro Oncol
Autors principals: Sahm, F., Korshunov, A., Jones, D. T. W., Paulus, W., Herold-Mende, C., Unterberg, A., Pfister, S. M., Brandner, S., Wick, W., von Deimling, A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
P09 Low grade gliomas
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782712/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.218
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