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ET-58 THE GENETICALLY ENGINEERED CLOSTRIDIUM NOVYI-NT IS EFFICACIOUS IN THE TREATMENT OF INTRACRANIAL GLIOBLASTOMAS

Glioblastomas (GBM) exhibit a remarkable histopathologic heterogeneity with extensive necrotic regions intermixed with cell proliferation that generate local hypoxia and thus, limit the effectiveness greatly of traditional cancer therapies. The spore-forming bacterium Clostridium spp., however, has...

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Autors principals: Staedtke, Verena, Bai, Renyuan, Kinzler, Kenneth, Zhou, Shibin, Vogelstein, Bert, Riggins, Gregory
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218154/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.55
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