ET-14 OPTIMISATION OF BORONOPHENYLALANINE (BPA) DELIVERY AND LAT1 EXPRESSION FOR THE CLINICAL APPLICATION OF BORON NEUTRON CAPTURE THERAPY (BNCT) IN GLIOBLASTOMA

BNCT is a biologically targeted radiotherapy where preferential boron uptake interacts with a neutron beam in cancerous cells causing irreparable alpha DNA damage. This requires the delivery of at least 30 parts per million (ppm) of 10B into tumour tissue and <10ppm 10B in healthy tissue. Renewed...

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Hlavní autoři: Cruickshank, Garth, Detta, Allah, Green, Stuart, Lockyer, Nick, Ngoga, Desire, Ghani, Zahir, Phoenix, Ben
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218109/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.14
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