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ET-11 RESVERATROL REGULATES GLIOBLASTOMA AND GLIOBLASTOMA STEM-LIKE CELLS VIA ANTI-TUMORIGENIC AKT DEPHOSPHORYLATION AND p53 ACTIVATION

Resveratrol (RES), a natural non-toxic plant product, exerts broad anti-cancer effects. RES was investigated for efficacy against glioblastoma (GBM) and therapeutically resistant GBM stem-like cells (GSC) hypothesized to drive tumor recurrence. Patient-derived GSC lines (12.1, 22, 33, 44) isolated v...

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Bibliografiske detaljer
Main Authors: Clark, Paul, Bhattacharya, Saswati, van Ginkel, Paul, Darjatmoko, Soesiawati, Elmayam, Ardem, Polans, Arthur, Kuo, John
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218106/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.11
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