Activation of Ca2+ signaling in neutrophils by the mast cell-released immunophilin FKBP12.

The immunophilins of the FK506-binding protein (FKBP) family are intracellular proteins that bind the immunosuppresants FK506 and rapamycin. In this study we show that HMC-1 mast cells sensitized with IgE release FKBP12 upon stimulation with anti-IgE. The release is rapid and not affected by actinom...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Bang, H, Müller, W, Hans, M, Brune, K, Swandulla, D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42181/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7536932/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.8.3435
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