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EG-05 COMBINATION OF GENE COPY GAIN AND EPIGENETIC DEREGULATION ARE ASSOCIATED WITH THE ABERRANT EXPRESSION OF A STEM CELL RELATED HOX-SIGNATURE IN GLIOBLASTOMA

We previously reported a stem cell related HOX gene signature associated with resistance to chemo-radiotherapy (TMZ/RT- > TMZ) in glioblastoma. However, underlying mechanisms triggering overexpression remain mostly elusive. Interestingly, HOX genes are neither involved in the developing brain, no...

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Bibliografiske detaljer
Main Authors: Kurscheid, Sebastian, Bady, Pierre, Sciuscio, Davide, Samarzija, Ivana, Shay, Tal, Vassallo, Irene, Van Criekinge, Wim, Domany, Eytan, Stupp, Roger, Delorenzi, Mauro, Hegi, Monika
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218099/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou254.5
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