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EG-05 COMBINATION OF GENE COPY GAIN AND EPIGENETIC DEREGULATION ARE ASSOCIATED WITH THE ABERRANT EXPRESSION OF A STEM CELL RELATED HOX-SIGNATURE IN GLIOBLASTOMA
We previously reported a stem cell related HOX gene signature associated with resistance to chemo-radiotherapy (TMZ/RT- > TMZ) in glioblastoma. However, underlying mechanisms triggering overexpression remain mostly elusive. Interestingly, HOX genes are neither involved in the developing brain, no...
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Main Authors: | , , , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Oxford University Press
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218099/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou254.5 |
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