The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence

Gene expression—based prediction of genomic copy number aberrations in the chromosomal region 12q13 to 12q15 that is flanked by MDM2 and CDK4 identified Wnt inhibitory factor 1 (WIF1) as a candidate tumor suppressor gene in glioblastoma. WIF1 encodes a secreted Wnt antagonist and was strongly downre...

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Detalles Bibliográficos
Main Authors: Lambiv, Wanyu L., Vassallo, Irene, Delorenzi, Mauro, Shay, Tal, Diserens, Annie-Claire, Misra, Anjan, Feuerstein, Burt, Murat, Anastasia, Migliavacca, Eugenia, Hamou, Marie-France, Sciuscio, Davide, Burger, Raphael, Domany, Eytan, Stupp, Roger, Hegi, Monika E.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
Assuntos:
Basic and Translational Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129269/
https://ncbi.nlm.nih.gov/pubmed/21642372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor036
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