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EG-03 EXPRESSION OF PRMT5 CORRELATES WITH MALIGNANT GRADE IN GLIOMAS AND PLAYS A PIVOTAL ROLE IN TUMOR GROWTH

Protein arginine methyltransferase 5 (PRMT5) catalyzes the formation of ω-NG,N′G-symmetric dimethylarginine residues on histones as well as other proteins. The modification play an important role in cell differentiation and tumor cell growth. However, the role of PRMT5 in human glioma cells has not...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Han, Xiaosi, Li, Rong, Zhang, Wenbin, Yang, Xiuhua, Fathallah-Shaykh, Hassan, Gillespie, Yancey, Nabors, Burt
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218097/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou254.3
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