Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitro

Protein arginine methyltransferase 5 (PRMT5) catalyzes the formation of ω-NG,N'G-symmetric dimethylarginine residues on histones as well as other proteins. These modifications play an important role in cell differentiation and tumor cell growth. However, the role of PRMT5 in human glioma cells...

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Détails bibliographiques
Auteurs principaux: Han, Xiaosi, Li, Rong, Zhang, Wenbin, Yang, Xiuhua, Wheeler, Crystal G., Friedman, Gregory K., Province, Paula, Ding, Qiang, You, Zhiying, Fathallah-Shaykh, Hassan M., Gillespie, G. Yancey, Zhao, Xinyang, King, Peter H., Nabors, L. Burt
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076054/
https://ncbi.nlm.nih.gov/pubmed/24664369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-014-1419-0
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