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CS-24 PYRUVATE KINASE M2-MEDIATED SUBCELLULAR LOCALIZATION OF HuR REGULATES GLIOMA GROWTH

HuR is an RNA-binding protein that influences the stability and translation of hundreds of different RNAs, and when overexpressed as in gliomas contribute to tumor formation. HuR, however, is typically localized to the nucleus, and the factors that regulate its export to the cytoplasm, and thus func...

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Detalhes bibliográficos
Main Authors: Mukherjee, Joydeep, Obha, Shigeo, Pieper, Russell
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217981/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou242.24
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