CB-15 NKCC1 REGULATES MIGRATION CAPACITY OF GLIOBLASTOMA TUMOR INITIATING CELLS BY MODULATING ACTIN CYTOSKELETON THROUGH SMALL RHO GTPASES

Glioblastoma (GBM) is a highly invasive and lethal brain tumor due to its high invasion and recurrence. The mechanisms that confer GBM cells their invasive behavior and their regulatory system have not been fully elucidated. We have shown that pharmacological inhibition and decreased expression of t...

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Main Authors: Schiapparelli, Paula, Magana-Maldonado, Roxana, Hamilla, Susan, Sibener, Leslie, Martinez-Gutierrez, Juan Carlos, Aranda-Espinoza, Helim, Quinones-Hinojosa, Alfredo
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217951/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou241.14
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