NKCC1 Regulates Migration Ability of Glioblastoma Cells by Modulation of Actin Dynamics and Interacting with Cofilin

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults. The mechanisms that confer GBM cells their invasive behavior are poorly understood. The electroneutral Na(+)-K(+)-2Cl(−) co-transporter 1 (NKCC1) is an important cell volume regulator that participates in cell migration. We hav...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Schiapparelli, Paula, Guerrero-Cazares, Hugo, Magaña-Maldonado, Roxana, Hamilla, Susan M., Ganaha, Sara, Goulin Lippi Fernandes, Eric, Huang, Chuan-Hsiang, Aranda-Espinoza, Helim, Devreotes, Peter, Quinones-Hinojosa, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514434/
https://ncbi.nlm.nih.gov/pubmed/28679472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.06.020
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