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AT-49 SAFETY EVALUATION OF HIGH-DOSE BCNU-LOADED BIODEGRADABLE IMPLANTS IN CHINESE PATIENTS WITH RECURRENT MALIGNANT GLIOMAS

OBJECTIVES: Malignant gliomas are common primary brain tumors with dismal prognosis. The blood-brain barrier and unacceptable systemic toxicity limit the employment of chemotherapeutic agents. BCNU-impregnated biodegradable polymers (Gliadel(®)) have been demonstrated to prolong the survival of pati...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Sai, Ke, Zhong, Ming-gu, Chen, Zhong-ping
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217828/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.48
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