A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma.

A previous placebo-controlled trial has shown that biodegradable 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) wafers (Gliadel wafers) prolong survival in patients with recurrent glioblastoma multiforme. A previously completed phase 3 trial, also placebo controlled, in 32 patients with newly diagnose...

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Detalhes bibliográficos
Main Authors: Westphal, Manfred, Hilt, Dana C., Bortey, Enoch, Delavault, Patrick, Olivares, Robert, Warnke, Peter C., Whittle, Ian R., Jääskeläinen, Juha, Ram, Zvi
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920672/
https://ncbi.nlm.nih.gov/pubmed/12672279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1522-8517-02-00023-6
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