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Transcriptional Interference Antagonizes Proviral Gene Expression to Promote HIV Latency
Eradication of the latent HIV reservoir remains a major barrier to curing AIDS. However, the mechanisms that direct viral persistence in the host are not well understood. Studying a model system of post-integration latency, we found that proviral integration into the actively transcribed host genes...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217705/ https://ncbi.nlm.nih.gov/pubmed/18692772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.05.016 |
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