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Transcriptional Interference Antagonizes Proviral Gene Expression to Promote HIV Latency

Eradication of the latent HIV reservoir remains a major barrier to curing AIDS. However, the mechanisms that direct viral persistence in the host are not well understood. Studying a model system of post-integration latency, we found that proviral integration into the actively transcribed host genes...

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Detalhes bibliográficos
Main Authors: Lenasi, Tina, Contreras, Xavier, Peterlin, B. Matija
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217705/
https://ncbi.nlm.nih.gov/pubmed/18692772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.05.016
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