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First (18)F-labeled ligand for PET imaging of uPAR: In vivo studies in human prostate cancer xenografts
Urokinase-type plasminogen activator receptor (uPAR) is overexpressed in human prostate cancer and uPAR has been found to be associated with metastatic disease and poor prognosis. AE105 is a small linear peptide with high binding affinity to uPAR. We synthesized an N-terminal NOTA-conjugated version...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217481/ https://ncbi.nlm.nih.gov/pubmed/23602763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2013.03.001 |
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