uPAR-targeted optical near-infrared (NIR) fluorescence imaging and PET for image-guided surgery in head and neck cancer: proof-of-concept in orthotopic xenograft model

PURPOSE: Urokinase-like Plasminogen Activator Receptor (uPAR) is overexpressed in a variety of carcinoma types, and therefore represents an attractive imaging target. The aim of this study was to assess the feasibility of two uPAR-targeted probes for PET and fluorescence tumor imaging in a human xen...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Christensen, Anders, Juhl, Karina, Persson, Morten, Charabi, Birgitte Wittenborg, Mortensen, Jann, Kiss, Katalin, Lelkaitis, Giedrius, Rubek, Niclas, von Buchwald, Christian, Kjær, Andreas
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362495/
https://ncbi.nlm.nih.gov/pubmed/28039488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14282
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