eIF4AIII enhances translation of nuclear cap-binding complex–bound mRNAs by promoting disruption of secondary structures in 5′UTR

It has long been considered that intron-containing (spliced) mRNAs are translationally more active than intronless mRNAs (identical mRNA not produced by splicing). The splicing-dependent translational enhancement is mediated, in part, by the exon junction complex (EJC). Nonetheless, the molecular me...

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Detalhes bibliográficos
Main Authors: Choe, Junho, Ryu, Incheol, Park, Ok Hyun, Park, Joori, Cho, Hana, Yoo, Jin Seon, Chi, Sung Wook, Kim, Min Kyung, Song, Hyun Kyu, Kim, Yoon Ki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217471/
https://ncbi.nlm.nih.gov/pubmed/25313076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409695111
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