Carregant...

Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations

The loss of conformational entropy is a major contribution in the thermodynamics of protein folding. However, accurate determination of the quantity has proven challenging. We calculate this loss using molecular dynamic simulations of both the native protein and a realistic denatured state ensemble....

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Baxa, Michael C., Haddadian, Esmael J., Jumper, John M., Freed, Karl F., Sosnick, Tobin R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217416/
https://ncbi.nlm.nih.gov/pubmed/25313044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407768111
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!